In the presence of ph4pbr or o-difluorobenzene, the fluoride ion not only replaces chlorine, but also replaces the nitro group in the activated nitrobenzene in dmso. According to the reaction conditions, polychlorobenzene reacts with potassium fluoride to form monofluorobenzene, difluorobenzene and trifluorobenzene. Perfluorobenzene and perfluoropyridine can be obtained by a chlorine-fluorine exchange reaction. The best results were obtained by heating the mixture of the pc-aromatic substrate and potassium fluoride at a high temperature without solvent. The substitution of halides by fluoride ions also occurs on alkyl halides, especially in the presence of Caf 2,8, but the use of polychlorinated chains becomes more difficult.
Potassium fluoride is widely used as a fluorinating reagent for preparing various organic fluorides. In polar aprotic solvents (such as DMF, DMSO or tetramethylene sulfoxide), aromatic or vinyl groups with electron withdrawing groups can be easily prepared by the exchange reaction of potassium fluoride with aromatic or vinyl chloride.
Highly active anhydrous potassium fluoride
Basic Information
Product name:Highly active anhydrous potassium fluorie
CAS No:7789-23-3d
Molecular formula::KF
Other name;Potassium fluoride, Anhydrous potassium fluoride
Molecular weight: 58.10
Appearance and character
White powder.
Application:
Mainly used in the synthesis of fluorine-containing pesticide intermediates, fluorine-containing pharmaceutical intermediates, glass engraving, welding materials and industrial anti-corrosion.
Product index
| Item | Standard |
| Content | ≥99.0% |
| Moisture | ≤0.30% |
| Free acid (in HF) | ≤0.05% |
| Free base (in KOH) | ≤0.05% |
| Chloride (Cl) | ≤0.10% |
| PH | 7.0-9.0% |
| Fluorosilicate | ≤0.05% |
| Sulfate | ≤0.02% |
Operational notes:
Closed operation, local exhaust. Operators must be specially trained to strictly follow the operating procedures. It is recommended that the operator wear a hood-type electric air filter type dust-proof respirator, wear a tape anti-drug, and wear latex gloves. Avoid dust. Avoid contact with acids. Lightly load and unload during handling to prevent damage to packaging and containers. Equipped with leakage emergency treatment equipment. Empty containers may be harmful residues.
